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PEEL Therapeutics Initiates Clinical Trial of PEEL-224 in Patients with Advanced Solid Tumors

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August 10, 2022 – SALT LAKE CITY, UTAH – Peel Therapeutics, an evolutionary-inspired, clinical-stage biotech company developing medicines for cancer and inflammatory diseases has initiated a first-in-human clinical study of PEEL-224 in patients with advanced solid tumors. This follows recent acceptance of the company’s Investigational New Drug (IND) Application by the U.S. Food and Drug Administration (FDA). PEEL-224 was developed from a medicine that originates from the leaves and stem of an ancient tree used for thousands of years in traditional Chinese medicine.

The company is evaluating PEEL-224, a novel topoisomerase I inhibitor, in a Phase 1 dose escalation, repeat-dose, multi-center, open-label study in patients with advanced solid tumors. The trial will evaluate the safety, tolerability, pharmacokinetics and preliminary antitumor activity of PEEL-224.

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