Clinicians frequently have patient care questions that go unanswered. Several online resources provide information to assist clinical decision making but current workflow limits their use.

OpenInfoButton is a novel, standards-based health information search tool that integrates with multiple EHR systems and allows clinicians to quickly answer clinical questions in real-time. The software uses contextual information stored within the patient’s electronic health record (EHR) and utilized keywords to anticipate questions and provide links to relevant information. This tool allows clinicians to conduct online medical knowledge resource searches easily from multiple sources. To date, the software includes almost 40 knowledge resources. OpenInfoButton has received Health Level Seven (HL7) Infobutton Standard certification, which is required for EHR certification in the United States.