SEROLOGIC ASSAYS TO DIRECT PERSONALIZED DEMYELINATING DISEASE TREATMENT

There are over 2 million people around the world who suffer from multiple sclerosis (MS). It can take a protracted period to identify the disease, and while there are more treatments to address MS than there were a decade ago, they often have serious side effects and none of the current treatments stop the disease.

University of Utah researchers have identified a series of bacteria whose presence is highly associated with demyelinating diseases, specifically MS. These bacteria have been used to create a set of microbial reagents for use in serologic assays to personalize antimicrobial treatment of MS. Treating MS with specific antibiotics to halt or prevent disease would significantly improve patient outcomes by treating the root cause with less serious side effects.